Institute for Pharmacy
Publications

Epigenetic signatures in surrogate tissues are able to assess cancer risk and indicate the efficacy of preventive measures

James E Barrett, Chiara Maria Herzog, Sepideh Aminzadeh-Gohari, Elisa Redl, Isma Ishaq Parveen, Julia Rothärmel, Julia Tevini, Daniela D Weber, Luca Catalano, Victoria E Stefan, Thomas K Felder, Peter Obrist, Twana Alkasalias, Kristina Gemzell-Danielsson, Roland Lang, Barbara Kofler, Martin Widschwendter

Evaluation of long-term prevention of microbiological contamination of sterile preparations in a controlled ISO class 5 environment and an uncontrolled environment using a closed-system drug transfer device

Robert Terkola, Chiara N.J. Pietrzak, Alexander S. Nebel

Pharmacophore-based virtual screening for different research questions

Florian Fischer

Virtual Screening of Pesticides for Potential Janus Kinase Inhibition

Florian Fischer, Veronika Temml, Daniela Brigitte Schuster

Microtubule inhibition as a proposed mechanism for the anthelmintic effect of phytochemicals isolated from Cicerbita alpina

Mark James Horgan, Ines Sigg, Ioanna Poulopoulou, Francisco J Rodriguez-Mejias, Eva Albertini, Pietro Fusani, Florian Fischer, Eftychia Martinidou, Daniela Schuster, Stefan Martens, Pidder Jansen Dürr, Matthias Gauly, Hermann Stuppner, Alexander Weiss, Veronika Temml, Bianka Siewert , Humans; Animals; Anthelmintics/pharmacology; Caenorhabditis elegans/drug effects; Plant Extracts/pharmacology; Phytochemicals/pharmacology; Microtubules/drug effects; Brassicaceae/chemistry;

The Cdk inhibitor dinaciclib as a promising anti-tumorigenic agent in biliary tract cancer

Celina Ablinger, Daniel Neureiter, Theresa Mähr, Christian Mayr, Tobias Kiesslich, Nicole Maeding, Irina Valenta, Maximilian Ardelt, Fabian Wilhelm, Elen Neureiter, Markus Ritter, Johanna Pachmayr, Petra Huber-Cantonati , Humans; Cell Proliferation/drug effects; Antineoplastic Agents/pharmacology; Cell Line, Tumor; Biliary Tract Neoplasms/drug therapy; Pyridinium Compounds/pharmacology; Indolizines/pharmacology; Cyclic N-Oxides/pharmacology; Bridged Bicyclo Compounds, Heterocyclic/pharmacology; Apoptosis/drug effects; Cyclin-Dependent Kinases/antagonists & inhibitors; Protein Kinase Inhibitors/pharmacology; Cell Survival/drug effects;

Ein Patient mit komplexen Gerinnungsstörungen

Olaf Rose, Dorothee Dartsch, Rolf Mesters , ANTIPHOSPHOLIPID SYNDROME; Immunthrombozytopenie; Medikationsmanagement;

Pharmacist Perspectives on Assisted Suicide

Stephanie Clemens, Maximilian Lombardini, Alina Braunstein, Stefan Deibl, Alexander Schmidt-Ilsinger, Johanna Pachmayr, Olaf Rose

Drug Shortages

Olaf Rose, Kreshnik Hoti, Blete Isufi, Matthias Wachinger, Johanna Pachmayr, Alexander Hartl, Heinz Giesen, Stephanie Clemens

Potential antiandrogenic effects of parabens and benzophenone-type UV-filters by inhibition of 3α-hydroxysteroid dehydrogenases

Manuel Kley, Simon Stücheli, Pamela Ruffiner, Veronika Temml, Stéphanie Boudon, Daniela Schuster, Alex Odermatt , Humans; HEK293 Cells; Parabens/toxicity; Benzophenones/toxicity; Sunscreening Agents/toxicity; Androgen Antagonists/pharmacology; Endocrine Disruptors/toxicity; Receptors, Androgen/metabolism; Hydroxysteroid Dehydrogenases/metabolism; Dihydrotestosterone/metabolism; Molecular Docking Simulation;

Cisplatin-Induced Hearing Loss, Oxidative Stress, and Antioxidants as a Therapeutic Strategy-A State-of-the-Art Review

Olaf Rose, Tim Croonenberg, Stephanie Clemens, Tobias Hinteregger, Stefanie Eppacher, Petra Huber-Cantonati, Marta Garcia-Miralles, Raffaella Liuni, Silvia Dossena , OXIDATIVE STRESS; ANTIOXIDANTS; CISPLATIN; cisplatin-induced hearing loss (CIHL); Hearing loss; Ototoxicity;

Total Synthesis and Configuration Assignment of (+)-Myxoquaterine-450

Johanna Löhr, Sabrina Ortmann, Alexander Popoff, Rolf Müller, Thorsten Bach

Von automatischen Insulin-Dosiersystemen und Do-it-yourself-Apps.

Olaf Rose, Janna Kalle, Dietmar Böcker , TYPE-1 DIABETES-MELLITUS; INSULIN-PUMP THERAPY;

Treatment of Parkinson's Disease Psychosis-A Systematic Review and Multi-Methods Approach

Olaf Rose, Sophia Huber, Eugen Trinka, Johanna Pachmayr, Stephanie Clemens , CLOZAPINE; Systematic review; Survey; Pharmacotherapy; Parkinson's disease psychosis; Multi-methods; Pimavanserin; Quetiapine;

Molecular Modeling of potential Pesticide Interactions with Janus Kinases: A Predictive Analysis

Florian Fischer, Veronika Temml, Daniela Brigitte Schuster , PESTICIDE EXPOSURE; PHARMACOPHORE-BASED DISCOVERY; JANUS KINASE; IMMUNOLOGY;

FREEING ENERGY: A CASE STUDY COMPARING ACCURACY AND EFFICIENCY OF ADVANCED MOLECULAR DYNAMICS METHODS WITH CHEAPER END-POINT METHODS

Moritz-Connor Schulte, Monika Pintar-Hitzl, Daniela Brigitte Schuster, Veronika Temml

Impact of 2-hydroxypropyl-β-cyclodextrin inclusion complex formation on dopamine receptor-ligand interaction - A case study

Lukas Zell, Thomas S. Hofer, Mario Schubert, Alexander Popoff, Anna Hoell, Moritz Marschhofer, Petra Huber-Cantonati, Veronika Temml, Daniela Schuster , 2-hydroxypropyl-beta-cyclodextrin; Dopamine receptor ligands; In silico; In vitro; Inclusion complex; Semi-empirical quantum chemistry;

Artificial intelligence to assist decision-making on pharmacotherapy

Michael Buecker, Kreshnik Hoti, Olaf Rose , Artificial Intelligence; Cardiology; Clinical decision support system; Medication review; Pharmacotherapy; Pharmacy practice;

Discovery of the Pendulisporaceae

Ronald Garcia, Alexander Popoff, Chantal D. Bader, Johanna Loehr, Sebastian Walesch, Christine Walt, Judith Boldt, Boyke Bunk, F. P. Jake Haeckl, Antonia P. Gunesch, Joy Birkelbach, Ulrich Nuebel, Thomas Pietschmann, Thorsten Bach, Rolf Mueller , BIOLOGY; BIOSYNTHESIS; GENES; MECHANISM; ANTIBIOTICS; CLUSTER; PERSPECTIVE; NATURAL-PRODUCTS; Streptomyces; Sorangicin;

A validated HPLC-MS/MS method for the quantification of systemic mifepristone after subcutaneous application in mice

Julia Tevini, Sepideh Aminzadeh-Gohari, Daniela D Weber, Luca Catalano, Victoria E Stefan, Elisa Redl, Chiara Herzog, Roland Lang, Martin Widschwendter, Thomas K Felder, Barbara Kofler