Receptor biochemistry and tumor metabolism
Publications

Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma

Tomas Duraj, Miriam Kalamian, Giulio Zuccoli, Joseph C. Maroon, Dominic P. D'Agostino, Adrienne C. Scheck, Angela Poff, Sebastian F. Winter, Jethro Hu, Rainer J. Klement, Alicia Hickson, Derek C. Lee, Isabella Cooper, Barbara Kofler, Kenneth A. Schwartz, Matthew C. L. Phillips, Colin E. Champ, Beth Zupec-Kania, Jocelyn Tan-Shalaby, Fabiano M. Serfaty, Egiroh Omene, Gabriel Arismendi-Morillo, Michael Kiebish, Richard Cheng, Ahmed M. El-Sakka, Axel Pflueger, Edward H. Mathews, Donese Worden, Hanping Shi, Raffaele Ivan Cincione, Jean Pierre Spinosa, Abdul Kadir Slocum, Mehmet Salih Iyikesici, Atsuo Yanagisawa, Geoffrey J. Pilkington, Anthony Chaffee, Wafaa Abdel-Hadi, Amr K. Elsamman, Pavel Klein, Keisuke Hagihara, Zsofia Clemens, George W. Yu, Athanasios E. Evangeliou, Janak K. Nathan, Kris Smith, David Fortin, Jorg Dietrich, Purna Mukherjee, Thomas N. Seyfried , CANCER; METABOLISM; PRECISION MEDICINE; GLIOBLASTOMA; Glutaminolysis; Research design; Warburg Effect;

The beneficial impact of ketogenic diets on chemically-induced colitis in mice depends on the diet's lipid composition

Kajs Hadzic, Andras Gregor, Barbara Kofler, Marc Pignitter, Kalina Duszka , INFLAMMATION; NUTRITION; KETOGENIC DIET; COLITIS; Lipids;

The metabolic sensor AMPK

William J. Smiles, Ashley J. Ovens, Jonathan S. Oakhill, Barbara Kofler , CANCER; EXERCISE; METABOLISM; AMPK; Signalling; mTORC1;

Overcoming immunosuppression in cancer

Victoria E. Stefan, Daniela D. Weber, Roland Lang, Barbara Kofler , CANCER; KETOGENIC DIET; Anti-tumor immune response; Immune checkpoint blockade; Immunometabolism;

A workflow to study cellular reactions to volatile organic compounds exposure <i>in vitro</i>

L. Parrakova, P. Monfort-Lanzas, J. Tevini, S. Vernardis, M. Hermann, S. Dubrac, H. Jakel, J. Zeisler, H. Hackl, T. K. Felder, J. Gostner

New developments in AMPK and mTORC1 cross-talk

William J. Smiles, Ashley J. Ovens, Bruce E. Kemp, Sandra Galic, Janni Petersen, Jonathan S. Oakhill

A validated HPLC-MS/MS method for the quantification of systemic mifepristone after subcutaneous application in mice

Julia Tevini, Sepideh Aminzadeh-Gohari, Daniela D Weber, Luca Catalano, Victoria E Stefan, Elisa Redl, Chiara Herzog, Roland Lang, Martin Widschwendter, Thomas K Felder, Barbara Kofler

BEATS - MIGRANE

Janine Zwicklhuber, Sarah Hochmann, Antri Stefani, Martin Wolf, Rodolphe Poupardin, Nicole Maeding, Stefan Leis, Daniela Weber, Julia Tevini, Barbara Kofler, Elisabeth Russe, Dirk Strunk

Deciphering the metabolic footprint of ketosisinducing diets in healthy mice

J. Tevini, D. D. Weber, T. K. Felder, B. Kofler, K. Duszka

Targeting cancer metabolism by ketogenic diet

D. D. Weber, S. Aminzadeh-Gohari, J. Tevini, J. Barret, C. Herzog, L. Catalano, V. Stefan, E. Redl, R. Lang, T. K. Felder, M. Widschwendter, B. Kofler

Systemic metabolic effects of medium-chain fatty acids supplementation

F. Sternberg, M. Wimmer, J. Arapovic, T. Hommel, V. Panteva, A. Gregor, K. Duszka, B. Kofler, V. Somoza, J. Koenig, A. Dunkel, E. Pohl

Anaplerotic Therapy Using Triheptanoin in Two Brothers Suffering from Aconitase 2 Deficiency

Maximilian Penkl, Johannes A Mayr, René G Feichtinger, Ralf Reilmann, Otfried Debus, Manfred Fobker, Anja Penkl, Janine Reunert, Stephan Rust, Thorsten Marquardt

Clinical, Neuroimaging, and Metabolic Footprint of the Neurodevelopmental Disorder Caused by Monoallelic HK1 Variants

Saskia B Wortmann, Rene G Feichtinger, Lucia Abela, Loes A van Gemert, Mélodie Aubart, Claire-Marine Dufeu-Berat, Nathalie Boddaert, Rene de Coo, Lara Stühn, Jasmijn Hebbink, Wolfram Heinritz, Julia Hildebrandt, Nastassja Himmelreich, Christoph Korenke, Anna Lehman, Thomas Leyland, Christine Makowski, Rafael Jenaro Martinez Marin, Pauline Marzin, Chris Mühlhausen, Marlène Rio, Agnes Rotig, Charles-Joris Roux, Manuel Schiff, Tobias B Haack, Steffen Syrbe, Stas A Zylicz, Christian Thiel, Maria Veiga da Cunha, Emile van Schaftingen, Matias Wagner, Johannes A Mayr, Ron A Wevers, Eugen Boltshauser, Michel A Willemsen

Glucose Metabolism as a Potential Therapeutic Target in Cytarabine-Resistant Acute Myeloid Leukemia

Joana Pereira-Vieira, Daniela D Weber, Sâmia Silva, Catarina Barbosa-Matos, Sara Granja, Rui Manuel Reis, Odília Queirós, Young H Ko, Barbara Kofler, Margarida Casal, Fátima Baltazar

Biallelic variants in Plexin B2 (PLXNB2) cause amelogenesis imperfecta, hearing loss and intellectual disability

CEL Smith, V. Laugel-Haushalter, U. Hany, S. Best, RL Taylor, JA Poulter, SB Wortmann, RG Feichtinger, JA Mayr, S. Al Bahlani, G. Nikolopoulos, A. Rigby, GC Black, CM Watson, S. Mansour, CF Inglehearn, AJ Mighell, A. Bloch-Zupan, , , EXPRESSION; FAMILY; NERVOUS-SYSTEM; GENETICS; RNA; Dentistry; Genetic Research; Medical; TRANSMEMBRANE; SEMAPHORINS;

Biallelic Cys141Tyr variant of SEL1L is associated with neurodevelopmental disorders, agammaglobulinemia, and premature death

Denisa Weis, Liangguang L Lin, Huilun H Wang, Zexin Jason Li, Katarina Kusikova, Peter Ciznar, Hermann M Wolf, Alexander Leiss-Piller, Zhihong Wang, Xiaoqiong Wei, Serge Weis, Katarina Skalicka, Gabriela Hrckova, Lubos Danisovic, Andrea Soltysova, Tingxuan T Yang, René Günther Feichtinger, Johannes A Mayr, Ling Qi , Humans; Animals; MICE; PROTEINS; ENDOPLASMIC-RETICULUM; Proteins/metabolism; Ubiquitin-Protein Ligases/genetics; Endoplasmic Reticulum-Associated Degradation; Agammaglobulinemia/genetics; Mortality, Premature; Synoviolin; Reticulum-associated degradation; Sel1l; Er-associated degradation;

Energy and macronutrient restriction regulate bile acid homeostasis

András Gregor, Valeriya Panteva, Stefan Bruckberger, Arturo Auñon-Lopez, Sara Blahova, Viktoria Blahova, Julia Tevini, Daniela D Weber, Barbara Kofler, Marc Pignitter, Kalina Duszka , Male; Animals; MICE; HOMEOSTASIS; KETOGENIC DIET; CALORIC RESTRICTION; Bile Acids and Salts/metabolism; Intestines; Liver/metabolism; Nutrients; Carbohydrates; Bile acids; Fasting; Intestine;

Mitochondriale Dysfunktion bei Praeklampsie (PE)

H. Jaksch-Bogensperger, S. Huber, D. Weghuber, JA Mayr, T. Fischer, BB Neumayer, D. Gharehbaghi, M. Brandstetter, C. Fazelnia, RG Feichtinger, T. Lehenauer

A model to study cellular responses to volatile organic compounds

L. Parrakova, P. Monfort-Lanzas, J. Tevini, S. Vernardis, M. Hermann, S. Dubrac, H. Jäkel, J. Zeisler, H. Hackl, TK Felder, JM Gostner

Role of Hydrogen Sulfide in Inflammatory Bowel Disease

Nathalie Stummer, René G Feichtinger, Daniel Weghuber, Barbara Kofler, Anna M Schneider , Crohn's disease (CD); hydrogen sulfide (H2S); inflammatory bowel disease (IBD); ulcerative colitis (UC);